• <th id="ynyxy"><pre id="ynyxy"></pre></th>

    <button id="ynyxy"><acronym id="ynyxy"><menuitem id="ynyxy"></menuitem></acronym></button>

      84605-18-5

      • Product Name:Cycloastragenol
      • Molecular Formula:C30H50O5
      • Molecular Weight:490.724
      • Appearance:Colorless needle crystal
      Inquiry

      Product Details

      Appearance:Colorless needle crystal

      Purity:99%

      Factory Supply Hot Sale 84605-18-5 Cycloastragenol with Safe Transportation

      • Molecular Formula:C30H50O5
      • Molecular Weight:490.724
      • Appearance/Colour:Colorless needle crystal 
      • Vapor Pressure:8.17E-18mmHg at 25°C 
      • Refractive Index:1.582 
      • Boiling Point:617.2 °C at 760 mmHg 
      • PKA:14.57±0.29(Predicted) 
      • Flash Point:327.1 °C 
      • PSA:90.15000 
      • Density:1.2 g/cm3 
      • LogP:4.43660 

      Cycloastragenol(Cas 84605-18-5) Usage

      Description

      Cycloastragenol is a triterpenoid isolated from various legume species in the genus Astragalus that is purported to have telomerase activation activity. TA-65 is capable to increase average telomere length and to decrease the percentage of critically short telomeres and DNA damage in MEFs that harbor critically short telomeres. The effects on telomerase appear to be in common with other triterpenoid saponins (ie, ginsenosides RG1 and Rg3). These compounds at concentrations from 1 to 20 μM were reported to protect against IL-1β-, H2O2-, and tert-butylhydroperoxide-induced senescence in human chondrocytes, endothelial progenitor cells and fibroblasts, respectively.

      Uses

      Cycloastragenol is an aglycone derivative of astragaloside IV found in the root of Korean Astragalus membranaceus.

      Definition

      ChEBI: A sapogenin that is the aglycone derivative of astragaloside IV, a major saponin extracted from the root of Astragalus membranaceus.

      InChI:InChI=1/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21+,22?,23?,26+,27-,28-,29?,30?/m0/s1

      84605-18-5 Relevant articles

      Structure of cyclochivinoside C from Astragalus chivensis

      Naubeev,Uteniyazov

      , p. 560 - 562 (2007)

      The new cycloartane glycoside cyclochivi...

      Cycloascauloside a from Astragalus caucasicus leaves

      Alaniya,Chkadua,Gigoshvili,Kemertelidze

      , p. 445 - 448 (2006)

      The new cycloartane glycoside cycloascau...

      The use of two-phase acid hydrolysis method of preparing ring [...] (by machine translation)

      -

      Paragraph 0024-0066, (2019/07/08)

      The invention belongs to the field of ph...

      Compositions and methods for skin conditioning

      -

      Page/Page column 21, (2016/02/26)

      Methods and cosmetic compositions for co...

      Triterpene glycosides from astragalus. Structure of cyclolehmanoside C from A. lehmannianus

      Zhanibekov,Naubeev,Uteniyazov,Bobakulov, Kh. M.,Abdullaev

      , p. 475 - 477 (2013/09/02)

      The structure of a new cycloartane trite...

      Flavonoid and cycloartane glycosides from seeds of Koelreuteria paniculata

      Sutiashvili,Alaniya,Mshvildadze,Skhirtladze,Pichette,Lavoie

      , p. 395 - 397 (2013/07/26)

      -

      84605-18-5 Process route

      20S,24R-epoxycycloartan-3,6,16,25-tetraol-3-O-β-D-(2'-O-acetyl)xylopyranosyl-6-O-β-D-xylopyranoside
      84883-00-1

      20S,24R-epoxycycloartan-3,6,16,25-tetraol-3-O-β-D-(2'-O-acetyl)xylopyranosyl-6-O-β-D-xylopyranoside

      D-xylose
      58-86-6

      D-xylose

      20(S),24(R)-epoxy-9β,19-cyclolanostan-3β,6α,16β,25-tetrol
      84605-18-5

      20(S),24(R)-epoxy-9β,19-cyclolanostan-3β,6α,16β,25-tetrol

      Conditions
      Conditions Yield
      Acidic conditions;
       
      astragaloside IV
      83207-58-3,84687-43-4

      astragaloside IV

      cycloastragenol
      84605-18-5,90865-25-1,104112-00-7,78574-94-4

      cycloastragenol

      Conditions
      Conditions Yield
      With hydrogenchloride; In methanol; at 20 ℃; for 168h;
      64%
      With hydrogenchloride; In methanol; at 20 ℃; for 168h;
      64%
      With hydrogenchloride; In ethanol; benzene; for 24h; Heating;
      30 mg
      With sulfuric acid; In methanol; for 3h;
      30 mg
      Multi-step reaction with 2 steps
      1: 47 mg / H2SO4 / methanol / 4 h / Heating
      2: 17 mg / H2SO4 / methanol / 4 h / Heating
      With sulfuric acid; In methanol;
       
      Multi-step reaction with 2 steps
      1: 58 mg / H2SO4 / methanol / 4 h / Heating
      2: 11 mg / H2SO4 / methanol; H2O / 4 h / Heating
      With sulfuric acid; In methanol; water;
       
      With water; Acidic conditions;
       
      astragaloside IV; With sodium periodate; In methanol; water; at 20 ℃;
      With sodium tetrahydroborate; In methanol; at 20 ℃; for 24h;
      With sulfuric acid; In methanol; water; for 24h; pH=2;
      384 mg
      With hydrogenchloride; In methanol; chloroform; water; at 20 ℃; for 144h; Concentration;
       

      84605-18-5 Upstream products

      • 88192-85-2
        88192-85-2

        Cycloaraloside A

      • 135101-62-1
        135101-62-1

        cyclocarposide

      • 134563-28-3
        134563-28-3

        cycloaraloside E

      • 142735-27-1
        142735-27-1

        Cycloaraloside F

      84605-18-5 Downstream products

      • 86541-79-9
        86541-79-9

        astragenol

      • 1255151-99-5
        1255151-99-5

        C37H54O6

      • 1255152-16-9
        1255152-16-9

        C44H67NO8

      • 1255151-95-1
        1255151-95-1

        C44H67NO8

      Relevant Products

      涩屋,高压监狱在线观看完整版,酷爱影院高清在线观看免费视频,禁欲电影第一季在线观看

    1. <th id="ynyxy"><pre id="ynyxy"></pre></th>

      <button id="ynyxy"><acronym id="ynyxy"><menuitem id="ynyxy"></menuitem></acronym></button>